Vitalistic principles are based upon:

Untestable entities

Vitalistic principles hinge on a life force believed to govern living beings that cannot be measured or tested directly with current methods. Because this life energy is beyond empirical verification, it is described as an untestable entity. In contrast, scientific frameworks rely on ideas that have been tested and supported by evidence, i.e., validated hypotheses or robust paradigms, not on something that cannot be tested.

Nulled hypotheses

The successful paradigm

Validated hypotheses

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